The Amulet Remote buttons transmit IR codes compatible with Microsoft's standard Media Center remote. Some HTPC systems come with their own remote that uses different codes, along with software to recognize the new codes. If you have such a system, and are using the iMon manager software, you can use the Settings page within iMon's setup to change the infra-red codeset back to the standard Microsoft codes. The setting is located under Remote Controller; see this screenshot for more details.